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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F8
All Species:
4.55
Human Site:
T553
Identified Species:
12.5
UniProt:
A0AVK6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0AVK6
NP_078956.2
867
94166
T553
T
T
H
S
S
K
A
T
G
S
K
D
S
T
D
Chimpanzee
Pan troglodytes
XP_508325
867
94169
T553
T
T
H
S
S
K
A
T
G
S
K
D
S
T
D
Rhesus Macaque
Macaca mulatta
XP_001095088
867
94195
A553
T
T
H
S
S
K
A
A
G
T
K
D
S
T
D
Dog
Lupus familis
XP_534087
864
93661
K550
V
C
P
T
P
S
S
K
A
T
R
S
K
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q58FA4
860
93258
Q546
S
P
T
V
C
P
T
Q
P
S
N
A
T
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506156
878
95490
K564
N
T
S
S
I
D
S
K
S
K
V
L
T
N
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084876
724
79575
K411
G
S
S
S
A
A
S
K
M
A
Q
L
A
A
I
Zebra Danio
Brachydanio rerio
XP_694311
917
100437
K604
S
S
V
G
S
P
S
K
M
Q
R
T
E
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321561
384
43173
G71
V
N
V
L
E
S
V
G
V
L
A
R
K
A
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.6
89.6
N.A.
83
N.A.
N.A.
73.8
N.A.
48
39.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
98.1
94.2
N.A.
88.5
N.A.
N.A.
82.1
N.A.
59.9
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
0
N.A.
6.6
N.A.
N.A.
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
20
N.A.
N.A.
26.6
N.A.
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
30.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
34
12
12
12
12
12
12
23
12
% A
% Cys:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
0
34
0
12
34
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
12
0
0
0
12
34
0
0
0
0
12
0
% G
% His:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
0
0
0
34
0
45
0
12
34
0
23
0
34
% K
% Leu:
0
0
0
12
0
0
0
0
0
12
0
23
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% M
% Asn:
12
12
0
0
0
0
0
0
0
0
12
0
0
12
0
% N
% Pro:
0
12
12
0
12
23
0
0
12
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
12
0
12
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
23
12
0
0
0
% R
% Ser:
23
23
23
56
45
23
45
0
12
34
0
12
34
0
12
% S
% Thr:
34
45
12
12
0
0
12
23
0
23
0
12
23
34
0
% T
% Val:
23
0
23
12
0
0
12
0
12
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _